Chair: Luisa Diomede
9:00 – 9:20 Patrizia Polverino de Laureto (Department of Pharmaceutical and Pharmacological Sciences, CRIBI Biotechnology Centre, University of Padova) Could polyphenol compounds be promising drugs for Parkinson’s Disease? 

9:20 – 9:40 Manuela Leri (Department of Experimental and Clinical Biomedical Sciences, University of Florence) EVOO polyphenols can relieve autophagy dysregulation in Alzheimer's disease.

9:40 – 10:00 Giulia Faravelli (Department of Molecular Medicine, University of Pavia) C. elegans expressing D76N beta-2microglobulin: a useful model for screening drug candidates targeting amyloidosis. 

10:00 – 10:20 Stefano Thellung (Section of Pharmacology, Department of Internal Medicine and Centre of Excellence for Biomedical Research, University of Genoa) Prion protein fragment 90-231 impairs autophagic flux in neuronal cultures inducing cell death. 

10:20 – 10:40 Andrea Danani (IDSIA- Dalle Molle Institute for Artificial Intelligence, Manno, Switzerland) Structural polymorphism of Alzheimer’s beta amyloid fibrils.

Chair: Martino Bolognesi
11:00 – 11:20 Ciro Cecconi (Department of Physics, Informatics and Mathematics, University of Modena and Reggio Emilia, and Institute of Nanoscience S3, CNR) Single-molecule studies of the molecular mechanisms underlying the chaperone activity of HSPB8.

11:20 – 11:40 Claudio Canale (Department of Physics, University of Genoa) Unexpected asymmetry in the aggregation of partially labeled peptides. 

11:40 – 12:00 Alberto Diaspro (Department of Physics, University of Genoa and Nanoscopy, IIT) Multi-Messenger Optical Microscopy to study biological macromolecules in cells. 

12:00 – 12:10 Luca Oberti (Department of Biosciences, University of Milan) Rationally designed mutant light chain highlights properties modulating the soluble toxicity 

12:10 – 12:15 Davide Odino (Department of Physics, University of Genoa) Trodusquemine induces changes in the properties of biomimetic membranes. 

12:15 – 12:20 Mattia Siri (Department of Pharmaceutical Sciences, University of Genoa) Inhibition of amyloid beta aggregation by multi-target compounds. 

12:20 Final discussion