13:00 – 13:10 Welcome from the Head of the Physics Department

Chair: Massimo Stefani
13:10 – 13:40 Marcus Fändrich (Institute of Protein Biochemistry, Ulm University) Cryo-EM structures of fibrils from systemic amyloidosis.

13:40 – 14:00 Stefano Ricagno (Department of Biosciences, University of Milan) Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.

14:00 – 14:20 Francesca Lavatelli (Fondazione IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia) Proteotoxicity of amyloidogenic cardiotropic light chains.

14:20 – 14:40 Giulia Fani (Department of Experimental and Clinical Biomedical Sciences, University of Florence) Identification of membrane Ca2+ channels activated by protein misfolded oligomers.

14:40 – 15:00 Maria Elena Regonesi (Department of Biotechnology and Bioscience, University of Milano-Bicocca) Characterization of CASA complex: role of HspB8 in protein quality control in Spinocerebellar Ataxia type 3 model.

Chair: Patrizia Polverino de Laureto
15:30 – 15:50 Valeria Crippa (Department of Pharmacological and Biomolecular Sciences, University of Milan) The clearance of aggregated TDP-43 responsible for ALS/FTD diseases 

15:50 – 16:10 Margherita Romeo (Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan) Investigating the spreading and toxicity of tau using C. elegans.

16:10 – 16:30 Chiara Maria Giulia De Luca (Fondazione IRCCS Istituto Neurologico Carlo Besta, Unit of Neurology 5 and Neuropathology, Milan) Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and Multiple System Atrophy.

Chair: Fabrizio Chiti
16:30 – 18:00 General discussion