Virginia Bazzurro
Reports
bazzurro_secondyearreport.pdf
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Bazzurro_ThirdYearReport.pdf
(118.7 KB)
Contacts
- virginia.bazzurro@unige.it
Research activity
My research activity concerns the study of the action of pharmacological molecules on GABAA receptors activated by the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in neurons in culture.
In particular, I study the activation and the modulation of these receptors in a well-defined region of a cell through the photorelease of caged neurotransmitters for controlling individual neuronal responses with a high spatial resolution thanks to the coupling of the electrophysiological technique of the patch-clamp with the confocal and two-photon microscopy.
Ricerca
Lista completa pubblicazioni IRIS
Pubblicazioni IRIS
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mGlu5 receptor negative allosteric modulation reduces the aberrant cellular reactivity and
neurotoxicity of reactive human astrocytes differentiated from fibroblast of SOD1 and
C9orf72 ALS patients
Anno: 2024
Autore/i: Tessitore, Sara; Torazza, Carola; Kumar, Mandeep; Bacchetti, Francesca; Ravera, Silvia; Musante, Ilaria; Scudieri, Paolo; Bonifacino, Tiziana; Frizzi, Benedetta; Angeli, Elena; Bazzurro, Virginia;... -
Super-resolution 3D maps to study the antisecretory factor's effects on different GABAa receptor subunits in rat cerebellar granule cells in vitro
Anno: 2023
Autore/i: Bazzurro, V; Gatta, E; Angeli, E; Cupello, A; Lange, S; Jennische, E; Robello, M; Diaspro, A -
Electrophysiological study of the effects of side products of RuBi-GABA uncaging on GABAA receptors in cerebellar granule cells
Anno: 2022
Autore/i: Gatta, Elena; Bazzurro, Virginia; Angeli, Elena; Salis, Annalisa; Damonte, Gianluca; Cupello, Aroldo; Robello, Mauro; Diaspro, Alberto -
Involvement of GABA(A) receptors containing alpha(6) subtypes in antisecretory factor activity on rat cerebellar granule cells studied by two-photon uncaging
Anno: 2022
Autore/i: Bazzurro, V; Gatta, E; Angeli, E; Cupello, A; Lange, S; Jennische, E; Robello, M; Diaspro, A -
Protein delivery to living cells by thermal stimulation for biophysical investigation
Anno: 2022
Autore/i: Torricella, Francesco; Barbieri, Letizia; Bazzurro, Virginia; Diaspro, Alberto; Banci, Lucia
Main publications
Antisecretory Factor Modulates GABAA Receptor Activity in Neurons
V. Bazzurro, E. Gatta, A. Cupello, S. Lange, M. Robello, Journal of Molecular Neuroscience 64, 312–320 (2018).