Giulia Pinto

PhD student
XXXIV CICLO
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Giulia Pinto

Reports

1st year report (125.58 KB)
2nd year report (61.01 KB)
3rd year report (62.33 KB)

Contacts

e-mail
pinto@fisica.unige.it

Research activity

The project which includes my research activity is about the deposition of films of organic molecules and biomolecules on inorganic substrates in order to develop sensitive and selective biosensors. In particular, I’m studying the functionalization of gold substrates with ultrathin films of DNA.

The aim of the research is to develop a biosensor able to detect specific nucleotides sequences (for example, short RNA sequences associated to pathologies or virus) or to recognize cancer biomarkers (through the immobilization of sensitive proteins), exploiting the hybridization mechanism between complementary strands of nucleic acids.

The main investigation methods are scanning probe nanolithography (through atomic force microscope), spectroscopic ellipsometry and X-Rays photoelectron spectroscopy, that allow to obtain information about structural, optical and chemical properties of the analyzed films.

Research at DIFI

Research groups

Main publications

Morphological and Mechanical Characterization of DNA SAMs Combining Nanolithography with AFM and Optical Methods

G. Pinto, P. Canepa, C. Canale, M. Canepa, O. Cavalleri, Materials, 13(13), 2888 (2020) doi: 10.3390/ma13132888

Reproducibility warning: The curious case of Polyethylene glycol 6000 and spheroid cell culture

S. Serrati, C. Martinelli, A. Palazzo, R. M. Iacobazzi, M. Perrone, R. Santoliquido, Q. K. Ong, Z. Luo, A. Bekdemir, G. Pinto et al., , PLoS ONE, 15(3): e0224002 (2020) doi: 10.1371/journal.pone.0224002.

Functionalizing gold with single strand DNA: novel insight into optical properties via combined spectroscopic ellipsometry and nanolithography measurements

G. Pinto, P. Parisse, I. Solano, P. Canepa, M. Canepa, L. Casalis, O. Cavalleri, Soft Matter, 15, 2463 (2019) doi: 10.1039/C8SM02589D