Ali Mohebi

PhD student
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Ali Mohebi



Research activity

Bimodal microscopy

I am a PhD student in Nanoscopy & NIC lab section of Nikon Centre (Nic @ IIT) at the Istituto Italiano Di Tecnolgia (IIT) in Genoa, Italy supervised by Prof. A. Diaspro. I am working on multimodal optical scanning microscopy of bio macromolecules. The idea is to exploit the possibility to tune the microscope across a large, almost unlimited, range of spatial and temporal resolution ranges by integrating different light-matter interactions. Focused on a home made two photon microscopy integrated with a label-free optical scanning microscopy of chromatin cell nuclei based on polarization-resolved imaging under phasor map data analysis.

Recently, as visiting researcher I was involved in Biophotonic Imaging group in department of health technology at Technical University of Denmark (DTU) in Copenhagen, Denmark. My research focuses on design, alignment and development a homemade two-photon excitation fluorescence (TPEF) laser-scanning microscope based on polarization effect with upgraded resolution to image anisotropies and score colorectal cancer cells in tissue and spheroid at sub-cellular level to provide a preliminary diagnosis under analytical methods using MATLAB, Java (ImageJ/Fiji).

Main publications

Review on Complete Mueller Matrix Optical Scanning Microscopy Imaging

Combined Approach using Circular Intensity Differential Scattering Microscopy under Phasor Map Data Analysis

Polarization Label-Free Microscopy Imaging of Biological Samples by Exploiting the Zeeman Laser Emission

Phasor map analysis to investigate Hutchinson–Gilford progeria cell under polarization-resolved optical scanning microscopy